Field of study
Research projects
Ongoing research projects
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Glyco-pathology in dry eye disease
The PhD project investigates how ocular mucin-proteins, and their glycosylation maintain a healthy tear film, while exploring their contribution to the development and progression of dry eye disease.
Publications and research
Scientific publications
Chang, Vincent; Lian, Isaac; Mahoney, Keira E.; Romano, Jeffrey;
Afshari, Ali Reza
; Chen, Ryan J.; Chen, Xiangjun; Fineide, Fredrik; Khan, Ayyad Zartasht; Utheim, Tor Paaske; Karlsson, Niclas G.; Laurie, Gordon W.; Malaker, Stacy A.
(2026).
Mapping galectin-3 ligands in human tear fluid establishes spliceoform-dependent lacritin binding.
Communications Biology.
https://doi.org/10.1038/s42003-026-10337-2
Afshari, Ali Reza
; Bello-Gonzalez, Marysol; Andersen, Ida E.; Nogueira, Rita M. Martins; Karlsson, Niclas
(2026).
Clinical Europium fluorescent based lectin assays for mucin O-glycomics.
Shukla, Arun K. (Ed.).
Methods in Enzymology.
Elsevier.
https://doi.org/10.1016/bs.mie.2026.03.012
Afshari, Ali Reza
; Chang, Vincent; Thomsson, Kristina A.; Höglund, Jennifer; Browne, Elizabeth N.; Karadzhov, George; Mahoney, Keira E.; Lucas, Taryn M.; Rangel-Angarita, Valentina; Ryberg, Henrik; Gidwani, Kamlesh; Pettersson, Kim; Rolfson, Ola; Björkman, Lena I.; Eisler, Thomas; Schmidt, Tannin A.; Jay, Gregory D.; Malaker, Stacy A.; Karlsson, Niclas
(2025).
Glycoproteoforms of Osteoarthritis-associated Lubricin in Plasma and Synovial Fluid.
Molecular & Cellular Proteomics.
Vol. 24.
https://doi.org/10.1016/j.mcpro.2025.100923
