Fields of study
Academic disciplines
Human and veterinary science physiology
Subject areas
Pharmacy Physiology Pharmacology Metabolism Diabetes Signal transduction Exercise Extracellular vesicles
Research groups
Research projects
Ongoing research projects
-
Extracellular vesicles as signaling factors from skeletal muscle cells
We research the role of extracellular vesicles as secreting factors from skeletal muscle, what they contain, and whether they can affect other cells.
Completed research projects
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Bacterial components and their effect on energy metabolism in human skeletal muscle cells
Obesity and type 2 diabetes are associated with changes in gut microbiota and disturbed energy metabolism. Is there a crosstalk between gut bacteria and host energy metabolism?
Publications and research
Scientific publications
Witczak, Oliwia
; Beajani, Siver; Seo, Seaung Hee; Løvsletten, Nils Gunnar; Skagen, Christine;
Myhrstad, Mari Charlotte Wik
;
Telle-Hansen, Vibeke
; Eide, Lars; Rustan, Arild Christian;
Aas, Vigdis
(2025).
Impact of Short-Chain Fatty Acids on Glucose, Fatty Acid and Leucine Metabolism in Primary Human Myotubes.
Endocrinology, Diabetes & Metabolism.
https://doi.org/10.1002/edm2.70042
Aas, Vigdis
; Øvstebø, Reidun; Brusletto, Berit; Aspelin, Trude; Trøseid, Anne-Marie Siebke; Qureshi, Saba; Eid, Desima Shitandi Otundo; Olstad, Ole Kristoffer; Nyman, Tuula Anneli; Foss Haug, Kari Bente
(2023).
Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation.
19 p.
Frontiers in Physiology.
Vol. 14.
https://doi.org/10.3389/fphys.2023.1143966
Mengeste, Abel Mulu; Nikolic, Natasa; Dalmao Fernandez, Andrea; Feng, Yuan Zeng; Nyman, Tuula Anneli; Kersten, Sander; Haugen, Fred; Kase, Eili Tranheim;
Aas, Vigdis
; Rustan, Arild Christian; Thoresen, G. Hege
(2022).
Insight Into the Metabolic Adaptations of Electrically Pulse-Stimulated Human Myotubes Using Global Analysis of the Transcriptome and Proteome.
21 p.
Frontiers in Physiology.
Vol. 13.
https://doi.org/10.3389/fphys.2022.928195
Tingstad, Ragna Husby; Norheim, Frode Amador; Haugen, Fred; Feng, Yuan Zeng;
Tunsjø, Hege
; Thoresen, G. Hege; Rustan, Arild Christian;
Charnock, Colin
;
Aas, Vigdis
(2021).
The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells.
13 p.
Scientific Reports.
Vol. 11.
https://doi.org/10.1038/s41598-021-03730-w
Aas, Vigdis
; Thoresen, G. Hege; Rustan, Arild; Lund, Jenny
(2020).
Substrate oxidation in primary human skeletal muscle cells is influenced by donor age.
Cell and Tissue Research.
Vol. 382.
https://doi.org/10.1007/s00441-020-03275-w
Nikolic, Natasa;
Aas, Vigdis
(2019).
Electrical pulse stimulation of primary human skeletal muscle cells.
Methods in molecular biology.
Vol. 1889.
https://doi.org/10.1007/978-1-4939-8897-6_2
Lund, Jenny; Ouwens, D. Margriet; Wettergreen, Marianne; Bakke, Siril Skaret; Thoresen, G. Hege;
Aas, Vigdis
(2019).
Increased glycolysis and higher lactate production in hyperglycemic myotubes.
14 p.
Cells.
Vol. 8.
https://doi.org/10.3390/cells8091101
Lund, Jenny;
Aas, Vigdis
; Tingstad, Ragna Husby; Van Hees, Alfons; Nikolic, Natasa
(2018).
Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism.
Scientific Reports.
Vol. 8.
https://doi.org/10.1038/s41598-018-28249-5
Nikolic, Natasa; Görgens, Sven W.; Thoresen, G. Hege;
Aas, Vigdis
; Eckel, Jürgen; Eckardt, Kristin
(2016).
Electrical pulse stimulation of cultured skeletal muscle cells as a model for in vitro exercise - possibilities and limitations.
Acta Physiologica.
Vol. 220.
https://doi.org/10.1111/apha.12830
Aas, Vigdis
;
Gedde-Dahl, Ane
; Tingstad, Ragna Husby;
Charnock, Colin
(2015).
Tarmfloraen - på helsa løs.
Norsk Farmaceutisk Tidsskrift (NFT).
Vol. 123.
http://hdl.handle.net/11250/2373786