Research projects
Ongoing research projects
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Glyco-pathology in dry eye disease
The PhD project investigates how ocular mucin-proteins, and their glycosylation maintain a healthy tear film, while exploring their contribution to the development and progression of dry eye disease.
Completed research projects
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Lacritin-incorporated nanoparticles as new and improved treatment of dry eye disease
We are developing the protein lacritin, which is found in tears, to become a medicine for dry eye disease.
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The ocular microbiota and its role in health and dry eye disease
Our aim is to identify microbial risk profiles for disease development and severity by in-depth characterizations of the ocular microbiota of dry eye disease sufferers.
Publications and research
Scientific publications
Kristensen, Anna Tostrup; Thune, Noora Helene; Khan, Qalbi;
Utheim, Tor Paaske
;
Hammer, Hugo Lewi
; Sehic, Amer
(2026).
Student perspectives on integrating basic and clinical dental sciences: insights from three dental schools in Norway.
Frontiers in Dental Medicine.
Vol. 7.
https://doi.org/10.3389/fdmed.2026.1746468
Fineide, Fredrik A.; Allen, Richard C.; Bohman, Elin Henriette; Tønseth, Kim Alexander;
Utheim, Tor Paaske
; Khan, Ayyad Ahmad Zartasht
(2025).
Minimizing Postoperative Scars in Epicanthoplasty: A Concise Review.
Journal of Cosmetic Dermatology.
Vol. 24.
https://doi.org/10.1111/jocd.70603
Boberg-Ans, Lars Christian; Boberg-Ans, Sophie; Khan, Ayyad Ahmad Zartasht; Allen, Richard; Tønseth, Kim Alexander; Bohman, Elin Henriette;
Utheim, Tor Paaske
; Fineide, Fredrik
(2025).
Minimizing Post-Operative Scars in External Dacryocystorhinostomy: A Literature Review.
Clinical Ophthalmology.
Vol. Volume 19.
https://doi.org/10.2147/opth.s532729
Fineide, Fredrik; Khan, Ayyad Ahmad Zartasht; Boberg-Ans, Lars Christian; Allen, Richard C.; Bohman, Elin; Tønseth, Kim Alexander;
Utheim, Tor Paaske
(2025).
Minimizing Postoperative Scars in Upper Eyelid Blepharoplasty: A Concise Review.
Surgeries.
Vol. 6.
https://doi.org/10.3390/surgeries6040093
Hiller, John Kim; Sandås, Elise Mørk; Rootwelt, Helge; Vassli, Anja Østeby; Lumi, Xhevat; Moe, Morten Carstens;
Utheim, Tor Paaske
; Elgstøen, Katja Benedikte Prestø; Petrovski, Goran
(2025).
Metabolic Deficiencies in the Vitreous of Diabetic Retinopathy: Exploring the Potential of Dietary Supplementation to Address Key Metabolite Imbalances.
Clinical Ophthalmology.
Vol. 19.
https://doi.org/10.2147/OPTH.S531638
Chang, Vincent; Mahoney, Keira E.; Lian, Isaac; Chen, Ryan; Chung, Nara;
Utheim, Tor Paaske
;
Karlsson, Niclas
; Malaker, Stacy A.
(2025).
In-depth analysis of the tear fluid glycoproteome reveals diverse lacritin glycosylation and spliceoforms.
Journal of Biological Chemistry.
Vol. 301.
https://doi.org/10.1016/j.jbc.2025.110580
Thune, Noora Helene; Kristensen, Anna Tostrup; Khan, Qalbi;
Utheim, Tor Paaske
;
Hammer, Hugo Lewi
; Sehic, Amer
(2025).
Retention of skull anatomy knowledge in dental education: a comparative study.
Frontiers in Dental Medicine.
Vol. 6.
https://doi.org/10.3389/fdmed.2025.1596610
Kärkkäinen, Virve; Saari, Toni; Rusanen, Minna; Uusitalo, Hannu; Leinonen, Ville; Thiede, Bernd; Kaarniranta, Kai; Koivisto, Anne M.;
Utheim, Tor Paaske
(2025).
Neuroinflammation Markers in Tear Fluid of Mild Alzheimer’s Disease.
Journal of Molecular Neuroscience.
Vol. 75.
https://doi.org/10.1007/s12031-025-02368-x
Hiller, John Kim; Sandås, Elise Mørk; Rootwelt, Helge; Vassli, Anja Østeby; Lumi, Xhevat; Moe, Morten Carstens;
Utheim, Tor Paaske
; Elgstøen, Katja Benedikte Prestø; Petrovski, Goran
(2025).
Metabolomic biomarkers in vitreous humor: unveiling the molecular landscape of diabetic retinopathy progression.
International Journal of Retina and Vitreous (IJRV).
Vol. 11.
https://doi.org/10.1186/s40942-025-00682-5
Kärkkäinen, Virve; Saari, Toni; Hannonen, Sanna; Rusanen, Minna; Lehtola, Juha Matti; Uusitalo, Hannu; Leinonen, Ville; Thiede, Bernd; Kaarniranta, Kai; Koivisto, Anne M.;
Utheim, Tor Paaske
(2025).
Altered tear fluid protein expression in persons with mild Alzheimer's disease in proteins involved in oxidative stress, protein synthesis, and energy metabolism.
Journal of Alzheimer's Disease.
Vol. 105.
https://doi.org/10.1177/13872877251326868