Research projects
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Lacritin-incorporated nanoparticles as new and improved treatment of dry eye disease
We are developing the protein lacritin, which is found in tears, to become a medicine for dry eye disease.
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The ocular microbiota and its role in health and dry eye disease
Our aim is to identify microbial risk profiles for disease development and severity by in-depth characterizations of the ocular microbiota of dry eye disease sufferers.
Publications and research
Scientific publications
Jensen, Per Graae; Nilsen, Christian; Gundersen, Morten; Gundersen, Kjell Gunnar; Potvin, Rick;
Gazerani, Parisa
; Chen, Xiangjun;
Utheim, Tor Paaske
; Utheim, Øygunn Aass
(2024).
A Preservative-Free Approach – Effects on Dry Eye Signs and Symptoms After Cataract Surgery.
13 p.
Clinical Ophthalmology.
Vol. 18.
https://doi.org/10.2147/OPTH.S446804
Tellefsen Nøland, Sara Julie Maria; Magnø, Morten Schjerven;
Utheim, Tor Paaske
; Chen, Xiangjun
(2024).
Sex Differences in the Prevalence of Meibomian Gland Dysfunction: A Mini Review.
Current Eye Research.
https://doi.org/10.1080/02713683.2023.2301325
Khan, Ayyad Ahmad Zartasht; Ueland, Hans Olav; Bohman, Elin Henriette; Tønseth, Kim Alexander;
Utheim, Tor Paaske
(2024).
Ektropion.
Tidsskrift for Den norske legeforening.
Vol. 144.
https://doi.org/10.4045/tidsskr.23.0309
Naqvi, Maria
; Fineide, Fredrik;
Utheim, Tor Paaske
;
Charnock, Colin
(2024).
Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients.
The ocular surface.
https://doi.org/10.1016/j.jtos.2024.02.002
Storås, Andrea; Magnø, Morten Schjerven; Fineide, Fredrik; Thiede, Bernd; Chen, Xiangjun; Strumke, Inga;
Halvorsen, Pål
;
Utheim, Tor Paaske
;
Riegler, Michael Alexander
(2023).
Identifying Important Proteins in Meibomian Gland Dysfunction with Explainable Artificial Intelligence.
IEEE International Symposium on Computer-Based Medical Systems.
https://doi.org/10.1109/CBMS58004.2023.00217
Muttuvelu, Danson Vasanthan; Cehofski, Lasse Jørgensen;
Utheim, Tor Paaske
; Chen, Xiangjun; Vorum, Henrik; Rasmussen, Marie Louise Roed; Heegaard, Steffen; Khan, Asif Manzoor; Abduljabar, Ahmed Basim; Honoré, Bent
(2023).
Tear film proteome changes following Tobradex<sup>®</sup> therapy in anterior blepharitis.
12 p.
Acta Ophthalmologica.
https://doi.org/10.1111/aos.15792
Lyngstadaas, Anne Viktoria; Olsen, Markus Vicente Tørud; Bair, Jeffrey; Yang, Menglu; Hodges, Robin R.;
Utheim, Tor Paaske
; Serhan, Charles N.; Dartt, Darlene Ann
(2023).
Anti-Inflammatory and Pro-Resolving Actions of the N-Terminal Peptides Ac2-26, Ac2-12, and Ac9-25 of Annexin A1 on Conjunctival Goblet Cell Function.
15 p.
American Journal of Pathology.
Vol. 193.
https://doi.org/10.1016/j.ajpath.2023.05.020
Muttuvelu, Danson Vasanthan; Cehofski, Lasse Jørgensen; Holtz, Jeppe;
Utheim, Tor Paaske
; Chen, Xiangjun; Vorum, Henrik; Heegaard, Steffen; Rasmussen, Marie Louise Roed; Khan, Asif Manzoor; Abduljabar, Ahmed Basim; Honoré, Bent
(2023).
Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN.
14 p.
International Journal of Molecular Sciences.
Vol. 24.
https://doi.org/10.3390/ijms242015115
Badian, Reza; Ekman, Linnéa;
Pripp, Are Hugo
;
Utheim, Tor Paaske
; Englund, Elisabet; Dahlin, Lars B.; Rolandsson, Olov; Lagali, Neil Satish
(2023).
Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes.
9 p.
Diabetes.
Vol. 72.
https://doi.org/10.2337/db22-0863
Tashbayev, Behzod; Chen, Xiangjun;
Utheim, Tor Paaske
(2023).
Chalazion Treatment: A Concise Review of Clinical Trials.
Current Eye Research.
Vol. 49.
https://doi.org/10.1080/02713683.2023.2279014