Norwegian version
Niclas Karlsson

Niclas Karlsson

About

Professor Niclas Karlsson’s research is focusing on the role of glycosylation in human health. Glycans are omnipresent in biological interfaces, including the glycocalyx on cell membranes, on mucosal surfaces that protects gastrointestinal, pulmonary and reproductive tracts and the joints in the muscoskeletal system. The group is applying state-of-the-art mass spectrometric and HPLC based glycomics and glycoproteomics of both N-linked and O-linked glycoproteins to identify pathological alteration of the glycosylation.

Databases:

UniCarb-DB (https://unicarb-db.expasy.org)

UniCarb-DR (https://unicarb-dr.glycosmos.org). 

Publications:

Pubmed (https://www.ncbi.nlm.nih.gov/myncbi/1-Wzd4_y7_JkD/bibliography/public/)

Twitter: UniCarb-DB@NG_Karlsson

Research projects

Ongoing research projects

Scientific publications

Kamounah, Sarah; Thomsson, Kristina A.; Sørensen, Christiane Elisabeth; Bennett, Eric Paul; Karlsson, Niclas ; Pedersen, Anne Marie Lynge (2024). Altered O-Glycans in stimulated whole saliva from patients with primary Sjögren’s syndrome and non-pSS sicca. Scientific Reports. Vol. 14.
https://doi.org/10.1038/s41598-024-79473-1

Takahashi, Yushi; Karlsson, Niclas ; Okuda, Shujiro; Aoki-Kinoshita, Kiyoko F. (2024). Cooperation of GlycoPOST and UniCarb-DR towards a comprehensive glycomics data repository workflow. Analytical and Bioanalytical Chemistry.
https://doi.org/10.1007/s00216-024-05673-3

Urban, James; Jin, Chunsheng; Thomsson, Kristina A.; Karlsson, Niclas ; Ives, Callum M.; Fadda, Elisa; Bojar, Daniel (2024). Predicting glycan structure from tandem mass spectrometry via deep learning. 9 p. Nature Methods. Vol. 21.
https://doi.org/10.1038/s41592-024-02314-6

Jin, Chunsheng; Venkatakrishnan, Vignesh; Thomsson, Kristina A.; Aoki, Nobuyuki P.; Shinmachi, Daisuke; Aoki-Kinoshita, Kiyoko F.; Hayes, Catherine A.; Lisacek, Frédérique; Karlsson, Niclas (2024). UniCarb-DB: An MS/MS Experimental Glycomic Fragmentation Database. 19 p. Methods in molecular biology. Vol. 2836.
https://doi.org/10.1007/978-1-0716-4007-4_6

Swisa, Avital; Kieckhaefer, Julia; Daniel, Scott G.; El-Mekkoussi, Hilana; Kolev, Hannah M.; Tigue, Mark; Jin, Chunsheng; Assenmacher, Charles-Antoine; Dohnalová, Lenka; Thaiss, Christoph A.; Karlsson, Niclas ; Bittinger, Kyle; Kaestner, Klaus H. (2024). The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation. Developmental Cell.
https://doi.org/10.1016/j.devcel.2024.05.006

Saldova, Radka; Thomsson, Kristina A.; Wilkinson, Hayden; Chatterjee, Maitrayee; Singh, Ashish K.; Karlsson, Niclas ; Knaus, Ulla G. (2024). Characterization of intestinal O-glycome in reactive oxygen species deficiency. PLOS ONE. Vol. 19.
https://doi.org/10.1371/journal.pone.0297292

Bechtella, Leïla; Chunsheng, Jin; Fentker, Kerstin; Ertürk, Güney R.; Safferthal, Marc; Polewski, Łukasz; Götze, Michael; Graeber, Simon Y.; Vos, Gaël M.; Struwe, Weston B.; Mall, Marcus A.; Mertins, Philipp; Karlsson, Niclas ; Pagel, Kevin (2024). Ion mobility-tandem mass spectrometry of mucin-type O-glycans. Nature Communications. Vol. 15.
https://doi.org/10.1038/s41467-024-46825-4

Acharya, Binayak; Tofthagen, Marthe ; Maciej-Hulme, Marissa Lucy ; Suissa, Michal Rachel; Karlsson, Niclas (2024). Limited support for a direct connection between prebiotics and intestinal permeability – a systematic review. Glycoconjugate Journal.
https://doi.org/10.1007/s10719-024-10165-8

Rustad, Cecilie F.; Backe, Paul Hoff; Jin, Chunsheng; Merckoll, Else; Tveten, Kristian; Maciej-Hulme, Marissa Lucy ; Karlsson, Niclas ; Prescott, Trine; Mørk Sandås, Elise; Woldseth, Berit; Elgstøen, Katja B. Prestø; Holla, Øystein Lunde (2024). A monoallelic UXS1 variant associated with short-limbed short stature. Molecular Genetics & Genomic Medicine. Vol. 12.
https://doi.org/10.1002/mgg3.2472

Elsaid, Khaled; Merriman, Tony R.; Rossitto, Leigh-Ana; Liu-Bryan, Ru; Karsh, Jacob; Phipps-Green, Amanda; Jay, Gregory D.; Elsayed, Sandy; Qadri, Marwa; Miner, Marin; Cadzow, Murray; Dambruoso, Talia J.; Schmidt, Tannin A.; Dalbeth, Nicola; Chhana, Ashika; Höglund, Jennifer; Ghassemian, Majid; Campeau, Anaamika; Maltez, Nancy; Karlsson, Niclas ; Gonzalez, David J.; Terkeltaub, Robert (2023). Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia. Arthritis & Rheumatology. Vol. 75.
https://doi.org/10.1002/art.42413





These publications are obtained from Cristin. The list may be incomplete