English version
Niclas Karlsson

Niclas Karlsson

Kort om

Professor Niclas Karlssons forskning fokuserer på rollen til glykosylering i menneskers helse. Glykaner er allestedsnærværende i biologiske grensesnitt, inkludert glykokalyx på cellemembraner, på slimhinneoverflater som beskytter mage-tarm-, lunge- og reproduktive kanaler og leddene i muskelskjelettsystemet. Gruppen bruker state-of-the-art massespektrometrisk og HPLC-basert glykomikk og glykoproteomikk av både N-linked og O-linked glykoproteiner for å identifisere patologisk endring av glykosyleringen.

Databaser:

UniCarb-DB (https://unicarb-db.expasy.org)

UniCarb-DR (https://unicarb-dr.glycosmos.org).

Publikationer:

Pubmed (https://www.ncbi.nlm.nih.gov/myncbi/1-Wzd4_y7_JkD/bibliography/public/)

Twitter: UniCarb-DB@NG_Karlsson

Publikasjoner og forskningsresultater

Vitenskapelige publikasjoner

Elsaid, Khaled; Merriman, Tony R.; Rossitto, Leigh-Ana; Liu-Bryan, Ru; Karsh, Jacob; Phipps-Green, Amanda; Jay, Gregory D.; Elsayed, Sandy; Qadri, Marwa; Miner, Marin; Cadzow, Murray; Dambruoso, Talia J.; Schmidt, Tannin A.; Dalbeth, Nicola; Chhana, Ashika; Höglund, Jennifer; Ghassemian, Majid; Campeau, Anaamika; Maltez, Nancy; Karlsson, Niclas ; Gonzalez, David J.; Terkeltaub, Robert (2023). Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia. Arthritis & Rheumatology. Vol. 75.
https://doi.org/10.1002/art.42413

De Marco Verissimo, Carolina; Cwiklinski, Krystyna; Nilsson, Jonas; Mirgorodskaya, Ekaterina; Jin, Chunsheng; Karlsson, Niclas ; Dalton, John P. (2023). Glycan Complexity and Heterogeneity of Glycoproteins in Somatic Extracts and Secretome of the Infective Stage of the Helminth Fasciola hepatica. Molecular & Cellular Proteomics. Vol. 22.
https://doi.org/10.1016/j.mcpro.2023.100684

Andersson, Elin; Tykesson, Emil; Lohmander, L. Stefan; Karlsson, Niclas ; Jin, Chunsheng; Mirgorodskaya, Ekaterina; Swärd, Per; Struglics, André (2023). Quantification of chondroitin sulfate, hyaluronic acid and N-glycans in synovial fluid – A technical performance study. Osteoarthritis and Cartilage Open. Vol. 5.
https://doi.org/10.1016/j.ocarto.2023.100380

Contessotto, Paolo; Spelat, Renza; Ferro, Federico; Vysockas, Vaidas; Krivickienė, Aušra; Jin, Chunsheng; Chantepie, Sandrine; Chinello, Clizia; Pauza, Audrys G.; Valente, Camilla; Rackauskas, Mindaugas; Casara, Alvise; Zigmantaitė, Vilma; Magni, Fulvio; Papy-Garcia, Dulce; Karlsson, Niclas ; Ereminienė, Eglė; Pandit, Abhay; Da Costa, Mark (2023). Reproducing extracellular matrix adverse remodelling of non-ST myocardial infarction in a large animal model. 16 s. Nature Communications. Vol. 14.
https://doi.org/10.1038/s41467-023-36350-1

Chahal, Gurdeep; Padra, Médea; Erhardsson, Mattias; Jin, Chunsheng; Quintana-Hayashi, Macarena; Venkatakrishnan, Vignesh; Padra, János Tamás; Stenbäck, Helen; Thorell, Anders; Karlsson, Niclas ; Lindén, Sara K. (2022). A Complex Connection Between the Diversity of Human Gastric Mucin O-Glycans, Helicobacter pylori Binding, Helicobacter Infection and Fucosylation. Molecular & Cellular Proteomics. Vol. 21.
https://doi.org/10.1016/j.mcpro.2022.100421

Huang, Shan; Thomsson, Kristina A.; Jin, Chunsheng; Ryberg, Henrik; Das, Nabangshu; Struglics, André; Rolfson, Ola; Björkman, Lena I.; Eisler, Thomas; Schmidt, Tannin A.; Jay, Gregory D.; Krawetz, Roman; Karlsson, Niclas (2022). Truncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1α: Interplay between O-linked glycosylation and inflammatory cytokines. Frontiers in Molecular Biosciences. Vol. 9.
https://doi.org/10.3389/fmolb.2022.942406

Luis, Ana S; Baslé, Arnaud; Byrne, Dominic P.; Wright, Gareth S. A.; London, James A.; Jin, Chunsheng; Karlsson, Niclas ; Hansson, Gunnar C.; Eyers, Patrick A.; Czjzek, Mirjam; Barbeyron, Tristan; Yates, Edwin A.; Martens, Eric C.; Cartmell, Alan (2022). Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota. 8 s. Nature Chemical Biology. Vol. 18.
https://doi.org/10.1038/s41589-022-01039-x

Kouka, Thukaa; Akase, Sachiko; Sogabe, Isami; Jin, Chunsheng; Karlsson, Niclas ; Aoki-Kinoshita, Kiyoko F. (2022). Computational Modeling of O-Linked Glycan Biosynthesis in CHO Cells. Molecules. Vol. 27.
https://doi.org/10.3390/molecules27061766

Wilkinson, Hayden; Thomsson, Kristina A.; Rebelo, Ana L.; Hilliard, Mark; Pandit, Abhay; Rudd, Pauline M.; Karlsson, Niclas ; Saldova, Radka (2021). The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's Disease. 11 s. Journal of Proteome Research. Vol. 20.
https://doi.org/10.1021/acs.jproteome.1c00219

Mateoui, Constantina; Vitiazeva, Varvara; Kristjansdottir, Björg; Weijdegård, Birgitta; Örnros, Jessica; Gallini, Radiosa; Kamali-Moghaddam, Masood; Sundfeldt, Karrin; Karlsson, Niclas (2021). Analysis of blood group antigens on MUC5AC in mucinous ovarian cancer tissues using in situ proximity ligation assay. 7 s. Glycobiology. Vol. 31.
https://doi.org/10.1093/glycob/cwab090





Publikasjonslisten er hentet ut av Cristin. Listen kan være ufullstendig