Field of study
Pharmacology Pharmacologic Actions
Research groups
Research projects
Completed research projects
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Clinical pharmacology of antiseizure medications
Pharmacological treatment is challenging and needs individualized monitoring.
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The effect of a digital patient intervention on self-reported adherence to medications
In this PhD project we will create and validate a self-reported adherence questionnaire and use this to evaluate the effect of a digital patient intervention designed to increase adherence to medications in a specific patient group.
Publications and research
Scientific publications
Gervin, Kristina; Kverneland, Magnhild; Nakken, Karl Otto; Rudi, Knut; Iversen, Per Ole;
Landmark, Cecilie Johannessen
; Selmer, Kaja Kristine
(2026).
DNA methylation of antiseizure medication metabolism genes and pharmacokinetic changes in adult epilepsy patients treated with the modified Atkins diet.
Genes & Nutrition.
Vol. 21.
https://doi.org/10.1186/s12263-026-00796-x
Landmark, Cecilie Johannessen
; Belkilani, Heba; Awad, Lilyana; Burns, Margrete Larsen; Gottås, André; Svendsen, Torleiv; Sætre, Erik
(2026).
Pharmacokinetic variability and complex two-way interactions with cenobamate in patients with refractory epilepsy.
Epilepsia.
https://doi.org/10.1002/epi.70184
Helmstaedter, Christoph; Alfstad, Kristin Åshild; Dahl-Hansen, Eline; Henning, Oliver Johannes;
Landmark, Cecilie Johannessen
; Kälviäinen, Reetta; Kyte, Eli B.; Marusic, Petr; Mula, Marco; Myren, Sverre; Peltola, Jukka; Rubboli, Guido; Strzelczyk, Adam; Jozwiak, Sergiusz; Lossius, Morten Ingvar
(2026).
Proceedings from ERN EpiCARE “BEYOND SEIZURES” meeting, Aalesund, Norway, May the 27th. Advancing holistic care for rare and complex epilepsies in adults.
Epilepsy & Behavior.
Vol. 178.
https://doi.org/10.1016/j.yebeh.2025.110879
McBride, Audrey; Henning, Oliver Johannes;
Landmark, Cecilie Johannessen
; Watkins, Lance; Tromans, Samuel; Basset, Paul; Triantafyllopoulou, Paraskevi; Shankar, Rohit
(2025).
Rescue epilepsy medication and training: A comparison between midazolam use, guidelines, clinical practice, and possibilities in the UK and Norway.
Epilepsia Open.
Vol. 10.
https://doi.org/10.1002/epi4.70145
Vinayan, Kollencheri Puthenveettil; Asadi-Pooya, Ali Akbar; Jyotsna, Aruna Setumadhava; Kumar, Nithya N.; Elsas, Siegward M.;
Landmark, Cecilie Johannessen
; Matsabisa, Motlalepula; Mesraoua, Boulenouar; O'Callaghan, Finbar; Thiele, Elizabeth; Zhang, Chunbo; Riney, Kate
(2025).
Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings—A survey from the ILAE Plant-Based Therapy Task Force.
Epilepsia.
Vol. 66.
https://doi.org/10.1111/epi.18622
Berman, Erez; Pariente, Gali; Erenburg, Natalia; Hamed, Roa’a;
Landmark, Cecilie Johannessen
; Kovo, Michal; Eyal, Sara
(2025).
Folate transfer across the placenta during late pregnancy in women with epilepsy: A cross-sectional, two-center study.
Epilepsia.
Vol. 66.
https://doi.org/10.1111/epi.18575
Landmark, Cecilie Johannessen
; Burns, Margrete Larsen; Heger, Katrine; Kjeldsen, Signe Flood; Johannessen, Svein Ivar; Sætre, Erik
(2025).
A precision approach to therapeutic drug monitoring of valproate to evaluate markers of toxicity.
Epilepsia.
Vol. 66.
https://doi.org/10.1111/epi.18508
Vinayan, Kollencheri Puthenveettil; Asadi-Pooya, Ali Akbar; Jyotsna, Aruna Setumadhava; Kumar, Nithya N; Elsas, Sigward-M;
Landmark, Cecilie Johannessen
; Matsabisa, Motlalepula; Mesraoua, Boulenouar; O`Callaghan, Finbar; Thiele, Elizabeth; Zhang, Chunbo; Riney, Kate
(2025).
Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings—A survey from the ILAE Plant-Based Therapy Task Force.
Epilepsia.
Vol. 66.
https://doi.org/https://pubmed.ncbi.nlm.nih.gov/40
Landmark, Cecilie Johannessen
; Sætre, Johan; Gottås, André; Wolden, Martha; M`Quaele, Tao; Kjeldsen, Signe Flood; Våtevik, Anne Katrine; Sætre, Erik; Svendsen, Torleiv; Burns, Margrete Larsen; Øiestad, Elisabeth Leere; Johannessen, Svein Ivar
(2025).
Pharmacokinetic variability and use of therapeutic drug monitoring of cannabidiol in patients with refractory epilepsy.
Epilepsia.
Vol. 66.
https://doi.org/10.1111/epi.18284
Larsen, Rønnaug; Karimi, Ala;
Krogstad, Tonje
;
Landmark, Cecilie Johannessen
;
Holm, Lene Berge
(2025).
High Medication Non-Adherence Rates and its Drivers in the General Population: A Cross-sectional Study Using the OMAS-37 Adherence Survey Tool.
INQUIRY (INQ).
Vol. 62.
https://doi.org/10.1177/00469580251321596