Kristine Hole

Scientific publications

Hole, Kristine; Gangsø, Sofie; Jensstuen, Åsa Tonette; Ormøy, Hanne Holte; Paulsen, Maren; Molden, Espen; Haslemo, Tore (2023). Effect of CYP2D6 genotype on duloxetine serum concentration. Basic & Clinical Pharmacology & Toxicology.
https://doi.org/10.1111/bcpt.13954

Hole, Kristine; Haslemo, Tore; Molden, Espen (2023). Impact of CYP2D6 Genotype on Paroxetine Serum Concentration. 5 p. Therapeutic Drug Monitoring. Vol. 45.
https://doi.org/10.1097/FTD.0000000000001096

Faraj, Pari; Størset, Elisabet; Hole, Kristine; Smith, Godfrey L; Molden, Espen; Dietrichs, Erik Sveberg (2023). Pro-arrhythmic effect of escitalopram and citalopram at serum concentrations commonly observed in older patients – a study based on a cohort of 19,742 patients. EBioMedicine. Vol. 95.
https://doi.org/10.1016/j.ebiom.2023.104779

Faraj, Pari; Hermansen, Astrid; Molden, Espen; Hole, Kristine (2022). Identification of Escitalopram Metabolic Ratios as Potential Biomarkers for Predicting CYP2C19 Poor Metabolizers. 8 p. Therapeutic Drug Monitoring. Vol. 44.
https://doi.org/10.1097/FTD.0000000000000991

Kvitne, Kine Eide; Hole, Kristine; Krogstad, Veronica; Wollmann, Birgit Malene Tovik; Wegler, Christine; Johnson, Line Kristin; Hertel, Jens Kristoffer; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Sandbu, Rune; Hjelmesæth, Jøran Sture; Skovlund, Eva; Christensen, Hege; Jansson-Löfmark, Rasmus; Åsberg, Anders; Molden, Espen; Robertsen, Ida (2022). Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range. 10 p. European Journal of Clinical Pharmacology. Vol. 78.
https://doi.org/10.1007/s00228-022-03336-9

Kvitne, Kine Eide; Robertsen, Ida; Skovlund, Eva; Christensen, Hege Staaland; Krogstad, Veronica; Wegler, Christine; Angeles, Philip Carlo Soriano; Wollmann, Birgit Malene Tovik; Hole, Kristine; Johnson, Line Kristin; Sandbu, Rune; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Hjelmesæth, Jøran; Jansson-Löfmark, Rasmus; Åsberg, Anders (2021). Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity – a non-randomized three-armed controlled trial. 13 p. Clinical and Translational Science (CTS).
https://doi.org/10.1111/cts.13142

Hole, Kristine; Arnestad, Marianne; Molden, Espen; Haslemo, Tore (2021). Dose-Dependent Inhibition of CYP2D6 by Bupropion in Patients with Depression. 4 p. Journal of Clinical Psychopharmacology. Vol. 41.
https://doi.org/10.1097/JCP.0000000000001387

Klaasen, Rolf; Bergan, Stein; Bremer, Sara; Hole, Kristine; Nordahl, Christine Berg; Andersen, Anders Mikal; Midtvedt, Karsten; Skauby, Morten Heier; Vethe, Nils Tore (2020). Pharmacodynamic assessment of mycophenolic acid in resting and activated target cell population during the first year after renal transplantation. British Journal of Clinical Pharmacology. Vol. 86.
https://doi.org/10.1111/bcp.14218

Gjestad, Caroline; Hole, Kristine; Haslemo, Tore; Diczfalusy, Ulf; Molden, Espen (2019). Effect of Grapefruit Juice Intake on Serum Level of the Endogenous CYP3A4 Metabolite 4β-Hydroxycholesterol—an Interaction Study in Healthy Volunteers. 7 p. AAPS Journal. Vol. 21.
https://doi.org/10.1208/s12248-019-0330-1

Hole, Kristine; Wollmann, Birgit Malene Tovik; Nguyen, Camilla; Haslemo, Tore; Molden, Espen (2018). Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker. Therapeutic Drug Monitoring. Vol. 40.
https://doi.org/10.1097/FTD.0000000000000518

Dissemination

Faraj, Pari; Størset, Elisabet; Hole, Kristine; Smith, Godfrey L; Molden, Espen; Dietrichs, Erik Sveberg (2023). Pro-arrhythmic effect of escitalopram and citalopram at serum concentrations commonly observed in the elderly – a study based on a cohort of 19 742 patients. Second Nordic Conference on Personalized Medicine. Finnish Society of Clinical Pharmacology.

Kvitne, Kine Eide; Hole, Kristine; Molden, Espen; Robertsen, Ida (2022). Response to: “Utility of endogenous 4β-hydroxycholesterol as a biomarker to assess cytochrome P 450 3A (CYP3A) activity: not quite ready for prime time”. European Journal of Clinical Pharmacology.
https://doi.org/10.1007/s00228-022-03387-y

Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders (2017). Response to: ‘Response to: Bodyweightadjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance’. British Journal of Clinical Pharmacology. Vol. 83.
https://doi.org/10.1111/bcp.13276

Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders (2017). Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance. British Journal of Clinical Pharmacology. Vol. 83.
https://doi.org/10.1111/bcp.13188