Kristine Hole

Scientific publications

Faraj, Pari; Hermansen, Astrid; Molden, Espen; Hole, Kristine (2022). Identification of Escitalopram Metabolic Ratios as Potential Biomarkers for Predicting CYP2C19 Poor Metabolizers. Therapeutic Drug Monitoring . Vol. 44.

Kvitne, Kine Eide; Hole, Kristine; Krogstad, Veronica; Wollmann, Birgit Malene Tovik; Wegler, Christine; Johnson, Line Kristin; Hertel, Jens Kristoffer; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Sandbu, Rune; Hjelmesæth, Jøran Sture; Skovlund, Eva; Christensen, Hege; Jansson-Löfmark, Rasmus; Åsberg, Anders; Molden, Espen; Robertsen, Ida (2022). Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range. European Journal of Clinical Pharmacology . Vol. 78.
http://hdl.handle.net/10852/94795

Kvitne, Kine Eide; Robertsen, Ida; Skovlund, Eva; Christensen, Hege Staaland; Krogstad, Veronica; Wegler, Christine; Angeles, Philip Carlo Soriano; Wollmann, Birgit Malene Tovik; Hole, Kristine; Johnson, Line Kristin; Sandbu, Rune; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Hjelmesæth, Jøran; Jansson-Löfmark, Rasmus; Åsberg, Anders (2021). Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity – a non-randomized three-armed controlled trial. 13 p. Clinical and Translational Science (CTS) .
http://hdl.handle.net/10852/87609

Hole, Kristine; Arnestad, Marianne; Molden, Espen; Haslemo, Tore (2021). Dose-Dependent Inhibition of CYP2D6 by Bupropion in Patients with Depression. Journal of Clinical Psychopharmacology . Vol. 41.

Klaasen, Rolf; Bergan, Stein; Bremer, Sara; Hole, Kristine; Nordahl, Christine Berg; Andersen, Anders Mikal; Midtvedt, Karsten; Skauby, Morten Heier; Vethe, Nils Tore (2020). Pharmacodynamic assessment of mycophenolic acid in resting and activated target cell population during the first year after renal transplantation. British Journal of Clinical Pharmacology . Vol. 86.

Gjestad, Caroline; Hole, Kristine; Haslemo, Tore; Diczfalusy, Ulf; Molden, Espen (2019). Effect of Grapefruit Juice Intake on Serum Level of the Endogenous CYP3A4 Metabolite 4β-Hydroxycholesterol—an Interaction Study in Healthy Volunteers. 7 p. AAPS Journal . Vol. 21.

Hole, Kristine; Wollmann, Birgit Malene Tovik; Nguyen, Camilla; Haslemo, Tore; Molden, Espen (2018). Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker. Therapeutic Drug Monitoring . Vol. 40.

Hole, Kristine; Heiberg, Petra Lybæk; Gjestad, Caroline; Mehus, Lise Larsen; Rø, Øyvind; Molden, Espen (2018). Elevated 4β‐hydroxycholesterol/cholesterol ratio in anorexianervosa patients. Pharmacology Research & Perspectives . Vol. 6.
http://hdl.handle.net/10852/72614

Hole, Kristine; Størset, Elisabet; Olastuen, Ane; Haslemo, Tore; Kro, Grete Birkeland; Midtvedt, Karsten; Åsberg, Anders; Molden, Espen (2017). Recovery of CYP3A Phenotype after Kidney Transplantation. Drug Metabolism And Disposition . Vol. 45.

Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders (2017). The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. British Journal of Clinical Pharmacology . Vol. 83.
http://hdl.handle.net/10852/61716

Dissemination

Kvitne, Kine Eide; Hole, Kristine; Molden, Espen; Robertsen, Ida (2022). Response to: “Utility of endogenous 4β-hydroxycholesterol as a biomarker to assess cytochrome P 450 3A (CYP3A) activity: not quite ready for prime time”. European Journal of Clinical Pharmacology .

Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders (2017). Response to: ‘Response to: Bodyweightadjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance’. British Journal of Clinical Pharmacology . Vol. 83.

Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders (2017). Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance. British Journal of Clinical Pharmacology . Vol. 83.