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Ansatteoversikt
Vigdis Aas

Vigdis Aas

Stillingstittel
  • professor
Besøksadresse
  • Pilestredet 50, 0167 Oslo
  • Kontornummer: L231A
Telefon
  • Mobil: +47 992 76 852
  • Kontor: +47 672 36 281
E-post
  • vigdis.aas@oslomet.no
Tilhørighet

Fagfelt

Farmasi   Fysiologi   Farmakologi   Metabolisme   Diabetes   Intracellulær signalformidling   Trening   Ekstracellulære vesikler

Forskningsgrupper

Forskningsprosjekter

Aktive forskningsprosjekter

Publikasjoner og forskningsresultater

Vitenskapelige publikasjoner

Katare, Parmeshwar Bajirao; Tingstad, Ragna Husby ; Beajani, Sivar T.; Indseth, Jørgen Pasjkurov; Telle-Hansen, Vibeke ; Myhrstad, Mari Charlotte Wik ; Rustan, Arild Christian; Eide, Lars; Witczak, Oliwia ; Aas, Vigdis (2025). Divergent effects of monomethyl branched-chain fatty acids on energy metabolism and insulin signaling in human myotubes. Journal of Lipid Research. Vol. 66.
https://doi.org/10.1016/j.jlr.2025.100764

Witczak, Oliwia ; Beajani, Siver; Seo, Seaung Hee; Løvsletten, Nils Gunnar; Skagen, Christine; Myhrstad, Mari Charlotte Wik ; Telle-Hansen, Vibeke ; Eide, Lars; Rustan, Arild Christian; Aas, Vigdis (2025). Impact of Short-Chain Fatty Acids on Glucose, Fatty Acid and Leucine Metabolism in Primary Human Myotubes. Endocrinology, Diabetes & Metabolism.
https://doi.org/10.1002/edm2.70042

Aas, Vigdis ; Øvstebø, Reidun; Brusletto, Berit; Aspelin, Trude; Trøseid, Anne-Marie Siebke; Qureshi, Saba; Eid, Desima Shitandi Otundo; Olstad, Ole Kristoffer; Nyman, Tuula Anneli; Haug, Kari Bente Foss (2023). Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation. Frontiers in Physiology. Vol. 14.
https://doi.org/10.3389/fphys.2023.1143966

Mengeste, Abel Mulu; Nikolic, Natasa; Fernandez, Andrea Dalmao; Feng, Yuan Zeng; Nyman, Tuula Anneli; Kersten, Sander; Haugen, Fred; Kase, Eili Tranheim; Aas, Vigdis ; Rustan, Arild Christian; Thoresen, G. Hege (2022). Insight Into the Metabolic Adaptations of Electrically Pulse-Stimulated Human Myotubes Using Global Analysis of the Transcriptome and Proteome. Frontiers in Physiology. Vol. 13.
https://doi.org/10.3389/fphys.2022.928195

Tingstad, Ragna Husby ; Norheim, Frode Amador; Haugen, Fred; Feng, Yuan Zeng; Tunsjø, Hege ; Thoresen, G. Hege; Rustan, Arild Christian; Charnock, Colin ; Aas, Vigdis (2021). The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells. Scientific Reports. Vol. 11.
https://doi.org/10.1038/s41598-021-03730-w

Aas, Vigdis ; Thoresen, G. Hege; Rustan, Arild; Lund, Jenny (2020). Substrate oxidation in primary human skeletal muscle cells is influenced by donor age. Cell and Tissue Research. Vol. 382.
https://doi.org/10.1007/s00441-020-03275-w

Lund, Jenny; Ouwens, D. Margriet; Wettergreen, Marianne; Bakke, Siril Skaret; Thoresen, G. Hege; Aas, Vigdis (2019). Increased glycolysis and higher lactate production in hyperglycemic myotubes. Cells. Vol. 8.
https://doi.org/10.3390/cells8091101

Nikolic, Natasa; Aas, Vigdis (2019). Electrical pulse stimulation of primary human skeletal muscle cells. Methods in molecular biology. Vol. 1889.
https://doi.org/10.1007/978-1-4939-8897-6_2

Lund, Jenny; Aas, Vigdis ; Tingstad, Ragna Husby ; Hees, Alfons Van; Nikolic, Natasa (2018). Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism. Scientific Reports. Vol. 8.
https://doi.org/10.1038/s41598-018-28249-5

Nikolic, Natasa; Görgens, Sven W.; Thoresen, G. Hege; Aas, Vigdis ; Eckel, Jürgen; Eckardt, Kristin (2016). Electrical pulse stimulation of cultured skeletal muscle cells as a model for in vitro exercise - possibilities and limitations. Acta Physiologica. Vol. 220.
https://doi.org/10.1111/apha.12830



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Forskningsrapporter

Aas, Vigdis (1998). Stimulation of human neutrophilic granulocytes with interferon-gamma. ISBN: 9788291061818. 115 s.



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Formidling

Aas, Vigdis (2023). Signaler fra kontraherende muskler. Lunsjseminar. Høgskolen Kristiania.

Foss, Kari Bente; Aas, Vigdis ; Hussein, Abdille; Hussain, Misbah; Brusletto, Berit Sletbakk; Olstad, Ole Kristoffer; Trøseid, Anne-Marie S.; Aspelin, Trude; Nyman, Tuula Anneli; Øvstebø, Reidun (2021). Extracellular vesicles from skeletal muscle cells isolated from extremely obese patients with and without type 2-diabetes show different protein- and miRNA-pattern. ISEV2021.

Hussain, Misbah; Qureshi, Saba; Foss, Kari Bente; Øvstebø, Reidun; Aas, Vigdis (2019). Characterization of extracellular vesicles from human skeletal muscle cells. NSFTs Vintermøte 2019. NSFT - norsk selskap for farmakologi og toksikologi.

Albakaa, Nora; Haugen, Fred; Aas, Vigdis (2018). Energy metabolism and myokine production in skeletal muscle cells. NSFTs Vintermøte. NSFT (Norsk selskap for farmakologi og toksikologi).

Kase, Eili Tranheim; Lund, Jenny; Feng, Yuan Zeng; Langleite, Torgrim Mikal; Aas, Vigdis ; Jensen, Jan S.; Birkeland, Kåre I.; Gulseth, Hanne Løvdal; Drevon, Christian A; Rustan, Arild; Thoresen, G. Hege (2013). Effect of exercise on fatty acid and glucose metabolism in cultured human myotubes. Diabetologia. Vol. 56.

Aas, Vigdis (2013). Human muscle cells and inflammation. SYSDIET Workshop 2013. SYSDIET.

Bakke, Siril Skaret; Feng, Yuan Zeng; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis (2012). Lower lipolysis to counteract the development of type 2 diabetes mellitus - evidence from myotubes established from extremely obese subjects. Diabetesforskningskonferansen 2012. Norges Diabetesforbund.

Bakke, Siril Skaret; Nikolic, Natasa; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis (2012). Altered energy metabolism in skeletal muscle cells derived from morbidly obese donors. Genetic and Molecular Basis of Obesity and Body Weight Regulation. Keystone.

Bakke, Siril Skaret; Damlien, Lisbeth; Hjelmesæth, Jøran; Aas, Vigdis (2012). Motstand mot insulinresistens? Hvorfor er noen pasienter med sykelig overvekt beskyttet mot insulinresistens og type 2-diabetes?. Diabetesforum. Vol. 1.

Bakke, Siril Skaret; Nikolic, Natasa; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis (2012). ALTERED ENERGY METABOLISM IN SKELETAL MUSCLE CELLS DERIVED FROM MORBIDLY OBESE INDIVIDUALS. European Congress on Obesity (ECO). The European Association for the Study of Obesity.



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