English version
Vigdis Aas

Vigdis Aas

Fagfelt

Farmasi   Fysiologi   Farmakologi   Metabolisme   Diabetes   Intracellulær signalformidling   Trening   Ekstracellulære vesikler

Forskningsprosjekter

Aktive forskningsprosjekter

Vitenskapelige publikasjoner

Stian, Christiansen ; Haug, Kari Bente Foss; Hussain, Misbah; Hussein, Abdille; Brusletto, Berit; Øvstebø, Reidun; Witczak, Oliwia ; Aas, Vigdis (2025). Comparative proteomics and micro-RNA analysis of skeletal muscle cell small extracellular vesicles - Unique profiles in cells from severely obese individuals with type 2 diabetes versus normal glucose tolerance. Frontiers in Physiology. Vol. 16.
https://doi.org/10.3389/fphys.2025.1696916

Katare, Parmeshwar Bajirao; Tingstad, Ragna Husby ; Beajani, Sivar T.; Indseth, Jørgen Pasjkurov; Telle-Hansen, Vibeke ; Myhrstad, Mari Charlotte Wik ; Rustan, Arild Christian; Eide, Lars; Witczak, Oliwia ; Aas, Vigdis (2025). Divergent effects of monomethyl branched-chain fatty acids on energy metabolism and insulin signaling in human myotubes. Journal of Lipid Research. Vol. 66.
https://doi.org/10.1016/j.jlr.2025.100764

Witczak, Oliwia ; Beajani, Siver; Seo, Seaung Hee; Løvsletten, Nils Gunnar; Skagen, Christine; Myhrstad, Mari Charlotte Wik ; Telle-Hansen, Vibeke ; Eide, Lars; Rustan, Arild Christian; Aas, Vigdis (2025). Impact of Short-Chain Fatty Acids on Glucose, Fatty Acid and Leucine Metabolism in Primary Human Myotubes. Endocrinology, Diabetes & Metabolism.
https://doi.org/10.1002/edm2.70042

Aas, Vigdis ; Øvstebø, Reidun; Brusletto, Berit; Aspelin, Trude; Trøseid, Anne-Marie Siebke; Qureshi, Saba; Eid, Desima Shitandi Otundo; Olstad, Ole Kristoffer; Nyman, Tuula Anneli; Haug, Kari Bente Foss (2023). Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation. Frontiers in Physiology. Vol. 14.
https://doi.org/10.3389/fphys.2023.1143966

Mengeste, Abel Mulu; Nikolic, Natasa; Fernandez, Andrea Dalmao; Feng, Yuan Zeng; Nyman, Tuula Anneli; Kersten, Sander; Haugen, Fred; Kase, Eili Tranheim; Aas, Vigdis ; Rustan, Arild Christian; Thoresen, G. Hege (2022). Insight Into the Metabolic Adaptations of Electrically Pulse-Stimulated Human Myotubes Using Global Analysis of the Transcriptome and Proteome. Frontiers in Physiology. Vol. 13.
https://doi.org/10.3389/fphys.2022.928195

Tingstad, Ragna Husby ; Norheim, Frode Amador; Haugen, Fred; Feng, Yuan Zeng; Tunsjø, Hege ; Thoresen, G. Hege; Rustan, Arild Christian; Charnock, Colin ; Aas, Vigdis (2021). The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells. Scientific Reports. Vol. 11.
https://doi.org/10.1038/s41598-021-03730-w

Aas, Vigdis ; Thoresen, G. Hege; Rustan, Arild; Lund, Jenny (2020). Substrate oxidation in primary human skeletal muscle cells is influenced by donor age. Cell and Tissue Research. Vol. 382.
https://doi.org/10.1007/s00441-020-03275-w

Lund, Jenny; Ouwens, D. Margriet; Wettergreen, Marianne; Bakke, Siril Skaret; Thoresen, G. Hege; Aas, Vigdis (2019). Increased glycolysis and higher lactate production in hyperglycemic myotubes. Cells. Vol. 8.
https://doi.org/10.3390/cells8091101

Nikolic, Natasa; Aas, Vigdis (2019). Electrical pulse stimulation of primary human skeletal muscle cells. Methods in molecular biology. Vol. 1889.
https://doi.org/10.1007/978-1-4939-8897-6_2

Lund, Jenny; Aas, Vigdis ; Tingstad, Ragna Husby ; Hees, Alfons Van; Nikolic, Natasa (2018). Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism. Scientific Reports. Vol. 8.
https://doi.org/10.1038/s41598-018-28249-5





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Forskningsrapporter

Aas, Vigdis (1998). Stimulation of human neutrophilic granulocytes with interferon-gamma. ISBN: 9788291061818. 115 s.
https://hdl.handle.net/11250/4080125



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Formidling

Aas, Vigdis (2023). Signaler fra kontraherende muskler. Lunsjseminar. Høgskolen Kristiania.
https://hdl.handle.net/11250/3247120

Foss, Kari Bente; Aas, Vigdis ; Hussein, Abdille; Hussain, Misbah; Brusletto, Berit Sletbakk; Olstad, Ole Kristoffer; Trøseid, Anne-Marie S.; Aspelin, Trude; Nyman, Tuula Anneli; Øvstebø, Reidun (2021). Extracellular vesicles from skeletal muscle cells isolated from extremely obese patients with and without type 2-diabetes show different protein- and miRNA-pattern. ISEV2021.
https://hdl.handle.net/11250/5115843

Hussain, Misbah; Qureshi, Saba; Foss, Kari Bente; Øvstebø, Reidun; Aas, Vigdis (2019). Characterization of extracellular vesicles from human skeletal muscle cells. NSFTs Vintermøte 2019. NSFT - norsk selskap for farmakologi og toksikologi.
https://hdl.handle.net/11250/4199076

Albakaa, Nora; Haugen, Fred; Aas, Vigdis (2018). Energy metabolism and myokine production in skeletal muscle cells. NSFTs Vintermøte. NSFT (Norsk selskap for farmakologi og toksikologi).
https://hdl.handle.net/11250/4818822

Kase, Eili Tranheim; Lund, Jenny; Feng, Yuan Zeng; Langleite, Torgrim Mikal; Aas, Vigdis ; Jensen, Jan S.; Birkeland, Kåre I.; Gulseth, Hanne Løvdal; Drevon, Christian A; Rustan, Arild; Thoresen, G. Hege (2013). Effect of exercise on fatty acid and glucose metabolism in cultured human myotubes. Diabetologia. Vol. 56.
https://hdl.handle.net/11250/4312741

Aas, Vigdis (2013). Human muscle cells and inflammation. SYSDIET Workshop 2013. SYSDIET.
https://hdl.handle.net/11250/4381760

Bakke, Siril Skaret; Feng, Yuan Zeng; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis (2012). Lower lipolysis to counteract the development of type 2 diabetes mellitus - evidence from myotubes established from extremely obese subjects. Diabetesforskningskonferansen 2012. Norges Diabetesforbund.
https://hdl.handle.net/11250/5221125

Bakke, Siril Skaret; Nikolic, Natasa; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis (2012). ALTERED ENERGY METABOLISM IN SKELETAL MUSCLE CELLS DERIVED FROM MORBIDLY OBESE INDIVIDUALS. European Congress on Obesity (ECO). The European Association for the Study of Obesity.
https://hdl.handle.net/11250/4676827

Aas, Vigdis ; Bakke, Siril Skaret; Nikolic, Natasa; Hjelmesæth, Jøran; Thoresen, G. Hege; Rustan, Arild (2012). Altered energy metabolism in skeletal muscle cells derived from morbidly obese subjects. EASD 48th Meeting. European Association for the Study of Diabetes.
https://hdl.handle.net/11250/4525507

Bakke, Siril Skaret; Nikolic, Natasa; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis (2012). Altered energy metabolism in skeletal muscle cells derived from morbidly obese donors. Genetic and Molecular Basis of Obesity and Body Weight Regulation. Keystone.
https://hdl.handle.net/11250/3428774





Publikasjonslisten er hentet ut av Nasjonalt vitenarkiv (NVA). Listen kan være ufullstendig.